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RBPJ

recombination signal binding protein for immunoglobulin kappa J region

Synonyme:
AOS3, CBF1, IGKJRB, IGKJRB1, KBF2, RBP-J, RBPJK, RBPSUH, SUH, csl
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(3516) Summary: The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Also, this protein can bind specifically to the recombination signal sequence of immunglobulin kappa type J segments. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2011]
  • Mouse(19664) recombination signal binding protein for immunoglobulin kappa J region
  • Rat(679028) recombination signal binding protein for immunoglobulin kappa J region
  • chicken(422802) recombination signal binding protein for immunoglobulin kappa J region
  • Horse(100055547) recombination signal binding protein for immunoglobulin kappa J region
  • domestic cat(101100207) recombination signal binding protein for immunoglobulin kappa J region
  • dog(479122) recombination signal binding protein for immunoglobulin kappa J region
  • domestic guinea pig(100716535) recombination signal binding protein for immunoglobulin kappa J region
  • naked mole-rat(101726624) recombination signal binding protein for immunoglobulin kappa J region
  • cow(767928) recombination signal binding protein for immunoglobulin kappa J region
  • sheep(101107196) recombination signal binding protein for immunoglobulin kappa J region

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-RBPJ antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
Anti-RBPJ Antibody, clone 2D10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human, mouse, rat
Anwendung
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Anti-RBP-Jk, clone 1F1 Antibody, clone 1F1, from rat,
Speziesreaktivität
drosophila, human
Anwendung
ChIP
electrophoretic mobility shift assay

immunoprecipitation (IP)
Anti-RBPJ antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
bovine, dog, guinea pig, horse, human, rabbit, rat
Anwendung
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-RBP-Jk Antibody, Chemicon®, from rabbit,
Speziesreaktivität
human, mouse
Anwendung
ChIP
immunohistochemistry

western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human RBPJ,
Spezies
human
MISSION® esiRNA, targeting mouse Rbpj,
Spezies
mouse