Direkt zum Inhalt
Merck

PARP2

poly (ADP-ribose) polymerase 2

Synonyme:
ADPRT2, ADPRTL2, ADPRTL3, ARTD2, PARP-2, pADPRT-2
Spezies:
Human PARP2 (10038), Mouse Parp2 (11546), Rat Parp2 (290027), Zebrafish parp2 (100007906), cow PARP2 (505828), Horse PARP2 (100072572), domestic cat PARP2 (101090944), dog PARP2 (475392), domestic guinea pig Parp2 (100720452), sheep PARP2 (101118027)
UniProtKB-ID:
Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8
Gen-ID:
  • Human(10038) Summary: This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jul 2008]
  • Mouse(11546) poly (ADP-ribose) polymerase family, member 2
  • Rat(290027) poly (ADP-ribose) polymerase 2
  • Zebrafish(100007906) poly (ADP-ribose) polymerase family, member 2
  • cow(505828) poly (ADP-ribose) polymerase 2
  • Horse(100072572) poly (ADP-ribose) polymerase 2
  • domestic cat(101090944) poly (ADP-ribose) polymerase 2
  • dog(475392) poly (ADP-ribose) polymerase 2
  • domestic guinea pig(100720452) poly (ADP-ribose) polymerase 2
  • sheep(101118027) poly (ADP-ribose) polymerase 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
HPA052003
Anti-PARP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
western blot
SAB2108489
Anti-PARP2, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
western blot
SAB1304746
ANTI-PARP2 (N-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Speziesreaktivität
mouse
Anwendung
western blot
P248
Monoclonal Anti-PARP antibody produced in mouse, clone C-2-10, ascites fluid,
Speziesreaktivität
hamster, mouse, primate, rat
Anwendung
ELISA
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot

Cell Lines

Produktnummer
Beschreibung
Spezies
CLLS1066
MCF10A CELLS PARP2 (-/-), ,
Spezies
human

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
H57807
4-Hydroxychinazolin, 98%,
Spezies
mouse
N7287
NU-1025, ≥97% (HPLC), solid,
Spezies
mouse

Proteins

Produktnummer
Beschreibung
Spezies
SRP0193
PARP2 Active human, recombinant, expressed in baculovirus infected insect cells, ≥60% (SDS-PAGE),
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
EHU025371
MISSION® esiRNA, targeting human PARP2,
Spezies
human
EMU020061
MISSION® esiRNA, targeting mouse Parp2,
Spezies
mouse