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NKX2-1

NK2 homeobox 1

Synonyme:
BCH, BHC, NK-2, NKX2.1, NKX2A, TEBP, TITF1, TTF-1, TTF1
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(7080) Summary: This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TFF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Apr 2011]
  • Mouse(21869) NK2 homeobox 1
  • Rat(25628) NK2 homeobox 1
  • chicken(395322) NK2 homeobox 1
  • dog(403940) NK2 homeobox 1
  • domestic cat(101091876) NK2 homeobox 1
  • naked mole-rat(101703474) NK2 homeobox 1

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Nkx2.1-Antikörper, Klon 8G7-G3-1, ascites fluid, clone 8G7-G3-1, Chemicon®,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-TTF1 (Thyroid transcription factor 1) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM373, purified immunoglobulin,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-Thyroid Transcription Factor-1 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP141, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
flow cytometry
immunohistochemistry
Monoclonal Anti-TITF1 antibody produced in mouse, clone 2F6, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot
Monoclonal Anti-Nkx2-1 Antibody Produced In Mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL14531, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot