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NCOR2

nuclear receptor corepressor 2

Synonyme:
CTG26, N-CoR2, SMAP270, SMRT, SMRTE, SMRTE-tau, TNRC14, TRAC, TRAC-1, TRAC1
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(9612) Summary: This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011]
  • Mouse(20602) nuclear receptor co-repressor 2
  • Rat(360801) nuclear receptor co-repressor 2
  • Zebrafish(561503) nuclear receptor co-repressor 2
  • chicken(416815) nuclear receptor corepressor 2
  • cow(538549) nuclear receptor corepressor 2
  • Horse(100059253) nuclear receptor corepressor 2
  • domestic cat(101083973) nuclear receptor corepressor 2
  • dog(486242) nuclear receptor corepressor 2
  • domestic guinea pig(100720194) nuclear receptor corepressor 2
  • naked mole-rat(101702626) nuclear receptor corepressor 2
  • sheep(101121042) nuclear receptor corepressor 2

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-NCOR2 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence

immunohistochemistry
Anti-SMRTe-Antikörper, Upstate®, from rabbit,
Speziesreaktivität
human
Anwendung
ChIP
immunocytochemistry

western blot
Anti-SMRT Antibody, clone 1SM-1E7, ascites fluid, clone 1SM-1E7, from mouse,
Speziesreaktivität
human, mouse, rat
Anwendung
western blot
ChIPAb+ SMRT - ChIP Validated Antibody and Primer Set, ascites fluid, from mouse,
Speziesreaktivität
human, mouse, rat
Anwendung
ChIP
electrophoretic mobility shift assay

immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot

Proteins

Produktnummer
Beschreibung
Spezies
NCOR2/SMRT human, recombinant, expressed in E. coli, ≥60% (SDS-PAGE),
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human NCOR2,
Spezies
human