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Merck

HLA-E

major histocompatibility complex, class I, E

Synonyme:
EA1.2, EA2.1, HLA-6.2, MHC, QA1
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(3133) Summary: HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq, Jul 2008]

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-HLA-E purified produced in mouse, ,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-HLA-E antibody produced in rabbit, ,
Speziesreaktivität
human
Anwendung
western blot
Anti-HLA-E antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
Monoclonal Anti-HLA-E antibody produced in mouse, clone MEM-E/08, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
flow cytometry
Monoclonal Anti-HLA-E antibody produced in mouse, clone MEM-E/06, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human, nonhuman primates
Anwendung
flow cytometry

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human HLA-E,
Spezies
human