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HAP1

huntingtin-associated protein 1

Synonyme:
HAP2, HIP5, HLP, hHLP1
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(9001) Summary: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(15114) huntingtin-associated protein 1
  • Rat(29430) huntingtin-associated protein 1
  • dog(607751) huntingtin-associated protein 1
  • cow(618422) huntingtin-associated protein 1
  • domestic cat(101088631) huntingtin-associated protein 1
  • sheep(101108406) huntingtin-associated protein 1

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Antibodies

Product Number
Beschreibung
Speziesreaktivität
Anwendung
Anti-HAP1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
western blot
Anti-HAP1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
western blot
Anti-HAP1 Antibody, clone 1B6, clone 1B6, from mouse,
Speziesreaktivität
mouse, rat
Anwendung
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-HAP1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot

esiRNA

Product Number
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Hap1,
Spezies
mouse
MISSION® esiRNA, targeting human HAP1,
Spezies
human