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Merck

GUCY2D

guanylate cyclase 2D, membrane (retina-specific)

Synonyme:
CORD5, CORD6, CYGD, GUC1A4, GUC2D, LCA, LCA1, RCD2, RETGC-1, ROS-GC1, ROSGC, retGC
Spezies:
Human GUCY2D (3000), Mouse Gucy2d (14918), Rat Gucy2d (113911), dog GUCY2D (403863), cow GUCY2D (282245), sheep GUCY2D (101120932)
UniProtKB-ID:
Q02846, Q6LEA7
Gen-ID:
  • Human(3000) Summary: This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq, Dec 2008]
  • Mouse(14918) guanylate cyclase 2d
  • Rat(113911) guanylate cyclase 2d
  • dog(403863) guanylate cyclase 2D, membrane (retina-specific)
  • cow(282245) guanylate cyclase 2D, membrane (retina-specific)
  • sheep(101120932) guanylate cyclase 2D, membrane (retina-specific)

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
SAB1412143
ANTI-GUCY2D antibody produced in mouse, clone 7E5, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence
western blot
MABN1598
Anti-RetGC-1/GUCY2D Antibody, clone 6D8.2, clone 6D8.2, from mouse,
Speziesreaktivität
human
Anwendung
western blot
SAB1412146
ANTI-GUCY2D antibody produced in mouse, clone 6D9, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot
SAB1412144
ANTI-GUCY2D antibody produced in mouse, clone 5E10, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot
SAB1412145
ANTI-GUCY2D antibody produced in mouse, clone 6E9, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
EMU195091
MISSION® esiRNA, targeting mouse Gucy2d,
Spezies
mouse