GRM1
glutamate receptor, metabotropic 1
Synonyme:
GPRC1A, MGLU1, MGLUR1, SCAR13
Spezies:
Human GRM1 (2911), Mouse Grm1 (14816), Rat Grm1 (24414), domestic guinea pig Grm1 (100730891), naked mole-rat Grm1 (101712477), Domestic Rabbit GRM1 (100356201), Zebrafish grm1 (100150246), dog GRM1 (484024), domestic cat GRM1 (101094104), cow GRM1 (540485) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(2911) Summary: This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
- Mouse(14816) glutamate receptor, metabotropic 1
- Rat(24414) glutamate receptor, metabotropic 1
- domestic guinea pig(100730891) glutamate receptor, metabotropic 1
- naked mole-rat(101712477) glutamate receptor, metabotropic 1
- Domestic Rabbit(100356201) glutamate receptor, metabotropic 1
- Zebrafish(100150246) glutamate receptor, metabotropic 1
- dog(484024) glutamate receptor, metabotropic 1
- domestic cat(101094104) glutamate receptor, metabotropic 1
- cow(540485) glutamate receptor, metabotropic 1
- Horse(100060603) glutamate receptor, metabotropic 1
- chicken(421614) glutamate receptor, metabotropic 1
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Small Molecule - Agonist
Small Molecule - Antagonist
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-Glutamate antibody produced in mouse, clone GLU-4, ascites fluid,
Speziesreaktivität
wide range
Anwendung
ELISA
Anti-GRM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-metabotroper Glutamatrezeptor-1α-Antikörper, Schmerzen, CT, Chemicon®, from rabbit,
Speziesreaktivität
human, monkey, rat
Anwendung
immunohistochemistry
western blot
western blot
Anti-Metabotropic Glutamate Receptor 1 Antibody, Chemicon®, from rabbit,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Small Molecule - Inhibitor
Produktnummer
Beschreibung
Spezies
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
Spezies
rat, human
Small Molecule - Mixed Agonist/Antagonist
Produktnummer
Beschreibung
Spezies
L-(+)-2-Amino-4-phosphonobutyric acid, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
Spezies
rat, human
L-Glutaminsäure, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Spezies
rat, human