CACNA1C
calcium channel, voltage-dependent, L type, alpha 1C subunit
Synonyme:
CACH2, CACN2, CACNL1A1, CCHL1A1, CaV1.2, LQT8, TS
Spezies:
Human CACNA1C (775), Mouse Cacna1c (12288), Rat Cacna1c (24239), Zebrafish cacna1c (170581), cow CACNA1C (408015), Horse CACNA1C (100049924), chicken CACNA1C (395891), domestic cat CACNA1C (101082923), dog CACNA1C (403516), naked mole-rat Cacna1c (101717129) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(775) Summary: This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. [provided by RefSeq, Oct 2012]
- Mouse(12288) calcium channel, voltage-dependent, L type, alpha 1C subunit
- Rat(24239) calcium channel, voltage-dependent, L type, alpha 1C subunit
- Zebrafish(170581) calcium channel, voltage-dependent, L type, alpha 1C subunit
- cow(408015) calcium channel, voltage-dependent, L type, alpha 1C subunit
- Horse(100049924) calcium channel, voltage-dependent, L type, alpha 1C subunit
- chicken(395891) calcium channel, voltage-dependent, L type, alpha 1C subunit
- domestic cat(101082923) calcium channel, voltage-dependent, L type, alpha 1C subunit
- dog(403516) calcium channel, voltage-dependent, L type, alpha 1C subunit
- naked mole-rat(101717129) calcium channel, voltage-dependent, L type, alpha 1C subunit
- domestic guinea pig(100135490) calcium channel, voltage-dependent, L type, alpha 1C subunit
- Goat(100861292) calcium channel, voltage-dependent, L type, alpha 1C subunit
- sheep(101116562) calcium channel, voltage-dependent, L type, alpha 1C subunit
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Small Molecule - Allosteric Modulator
Produktnummer
Beschreibung
Spezies
Gabapentin -Lösung, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Gabapentin -Lösung, 10 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Small Molecule - Antagonist
Produktnummer
Beschreibung
Spezies
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Calcium Channel (α1C Subunit) (L-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rabbit, rat
Anwendung
immunohistochemistry
western blot
western blot
Anti-Calciumkanal-Antikörper, spannungsgesteuert, α 1C, Chemicon®, from rabbit,
Speziesreaktivität
human, mouse, rabbit, rat
Anwendung
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-CACNA1C antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot
western blot
Anti-Calcium Channel (Cardiac α1C Subunit) (L-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Speziesreaktivität
rabbit, rat
Anwendung
immunoprecipitation (IP)
western blot
western blot
Anti-Cav1.2 alpha1c, clone 8F9.1 Antibody, clone 8F9.1, from mouse,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
western blot
Small Molecule - Blocker
Produktnummer
Beschreibung
Spezies
Amlodipinbesilat, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human