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BAX

BCL2-associated X protein

Synonyme:
BCL2L4
Spezies:
Human BAX (581), Mouse Bax (12028), Rat Bax (24887), naked mole-rat Bax (101713575), domestic guinea pig Bax (100730890), Goat BAX (100846984), sheep BAX (443059), dog BAX (403523), domestic cat BAX (493837), cow BAX (280730)
UniProtKB-ID:
Q07812, A8K4W1, P55269, Q07814, Q07815, Q8WZ49, Q9NR76, Q9NYG7
Gen-ID:
  • Human(581) Summary: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(12028) BCL2-associated X protein
  • Rat(24887) Bcl2-associated X protein
  • naked mole-rat(101713575) BCL2-associated X protein
  • domestic guinea pig(100730890) BCL2-associated X protein
  • Goat(100846984) BCL2-associated X protein
  • sheep(443059) BCL2-associated X protein
  • dog(403523) BCL2-associated X protein
  • domestic cat(493837) BCL2-associated X protein
  • cow(280730) BCL2-associated X protein

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
ABC11
Anti-Bax (NT)-Antikörper, from rabbit,
Speziesreaktivität
bovine, canine, chimpanzee, feline, human, rhesus monkey
Anwendung
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
MAB4601
Anti-Bax-Antikörper, NT, aa3-16-hBax-Protein, Klon 2D2, clone 2D2, Chemicon®, from mouse,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
western blot
ZRB1103
Anti-Bax Antibody, clone 1C7, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human
Anwendung
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
SAB5700071
Anti-BAX antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
immunoprecipitation (IP)
western blot
WH0000581M1
Monoclonal Anti-BAX antibody produced in mouse, clone 1F5-1B7, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence
immunohistochemistry
proximity ligation assay
western blot

Cell Lines

Produktnummer
Beschreibung
Spezies
CLLS1006
SW48 Cells BAX -/-, ,
Spezies
human
CLLS1001
DLD1 Cells BAX -/-, ,
Spezies
human
CLLS1005
DLD1 Cells BAX/BAK (-/-,-/-), ,
Spezies
human
CLLS1011
SW48 Cells BAX/BAK (-/-,-/-), ,
Spezies
human

Proteins

Produktnummer
Beschreibung
Spezies
SRP5166
BAX, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
EHU069421
MISSION® esiRNA, targeting human BAX,
Spezies
human