BACE1
beta-site APP-cleaving enzyme 1
Synonyme:
ASP2, BACE, HSPC104
Spezies:
Human BACE1 (23621), Mouse Bace1 (23821), Rat Bace1 (29392), Zebrafish bace1 (403005), cow BACE1 (614333), Horse BACE1 (100071137), domestic cat BACE1 (101086840), dog BACE1 (489390), chicken BACE1 (419768), sheep BACE1 (101119667) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(23621) Summary: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
- Mouse(23821) beta-site APP cleaving enzyme 1
- Rat(29392) beta-site APP cleaving enzyme 1
- Zebrafish(403005) beta-site APP-cleaving enzyme 1
- cow(614333) beta-site APP-cleaving enzyme 1
- Horse(100071137) beta-site APP-cleaving enzyme 1
- domestic cat(101086840) beta-site APP-cleaving enzyme 1
- dog(489390) beta-site APP-cleaving enzyme 1
- chicken(419768) beta-site APP-cleaving enzyme 1
- sheep(101119667) beta-site APP-cleaving enzyme 1
- Domestic Rabbit(100343442) beta-site APP-cleaving enzyme 1
- naked mole-rat(101701890) beta-site APP-cleaving enzyme 1
- domestic guinea pig(100135485) beta-site APP cleaving enzyme 1
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ELISA
Produktnummer
Beschreibung
Spezies
Activity Assay
Produktnummer
Beschreibung
Spezies
β-Secretase (BACE1) Activity Detection Kit (Fluorescent), 1 kit sufficient for 250 reactions,
Spezies
human
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-BACE1 Antibody, clone 3D5, ,
Speziesreaktivität
human, mouse
Anwendung
ELISA
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
Anti-BACE 1, N-Terminus (46-62) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
western blot
Anti-BACE-Antikörper, CT, Klon 61-3E7, clone 61-3E7, Chemicon®, from mouse,
Speziesreaktivität
human, mouse, primate, rat
Anwendung
immunoprecipitation (IP)
western blot
western blot
Anti-BACE 1, C-Terminus (485-501) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
microarray
western blot
western blot
Anti-BACE1 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Anwendung
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Kits
Produktnummer
Beschreibung
Spezies
β-Secretase (BACE1) Activity Detection Kit (Fluorescent), 1 kit sufficient for 250 reactions,
Spezies
human
Proteins
Produktnummer
Beschreibung
Spezies
β-Secretase human, recombinant, expressed in HEK 293 cells (C-terminal FLAG tagged), extracellular domain, ≥10,000 units/mg protein, ≥90% (SDS-PAGE), buffered aqueous solution,
Spezies
human