APC
adenomatous polyposis coli
Synonyme:
BTPS2, DP2, DP2.5, DP3, GS, PPP1R46
Spezies:
Human APC (324), Mouse Apc (11789), Rat Apc (24205), sheep APC (101104664), domestic guinea pig Apc (100723694), naked mole-rat Apc (101704055), Zebrafish apc (386762), fruit fly Apc (44642), cow APC (533233), Horse APC (100064431) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(324) Summary: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008]
- Mouse(11789) adenomatosis polyposis coli
- Rat(24205) adenomatous polyposis coli
- sheep(101104664) adenomatous polyposis coli
- domestic guinea pig(100723694) adenomatous polyposis coli
- naked mole-rat(101704055) adenomatous polyposis coli
- Zebrafish(386762) adenomatosis polyposis coli
- fruit fly(44642) APC-like
- cow(533233) adenomatous polyposis coli
- Horse(100064431) adenomatous polyposis coli
- domestic cat(101096138) adenomatous polyposis coli
- dog(479139) adenomatous polyposis coli
- chicken(415607) adenomatous polyposis coli
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-APC Antibody, clone CC-1, clone CC-1, from mouse,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-APC antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-APC (Ab-1) Mouse mAb (FE9), liquid, clone FE9, Calbiochem®,
Speziesreaktivität
human, mouse, rat
Anwendung
Anti-APC Antibody, clone FE9, clone FE9, from mouse,
Speziesreaktivität
human
Anwendung
western blot
Anti-APC (C-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Cell Lines
Produktnummer
Beschreibung
Spezies