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ANK2

ankyrin 2, neuronal

Synonyme:
ANK-2, LQT4, brank-2
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(287) Summary: This gene encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. The protein encoded by this gene is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4 and cardiac arrhythmia syndrome. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2011]
  • Mouse(109676) ankyrin 2, brain
  • Rat(362036) ankyrin 2, neuronal
  • fruit fly(38863) Ankyrin 2
  • Horse(100064198) ankyrin 2, neuronal
  • domestic cat(101100129) ankyrin 2, neuronal
  • chicken(422689) ankyrin 2, neuronal
  • dog(487908) ankyrin 2, neuronal
  • sheep(101115623) ankyrin 2, neuronal
  • domestic guinea pig(100717265) ankyrin 2, neuronal
  • naked mole-rat(101697466) ankyrin 2, neuronal

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-ANK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-ANK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-Ankyrin B - Fitc antibody produced in mouse, clone S105-13, purified immunoglobulin,
Speziesreaktivität
human, mouse, rat
Anwendung
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-Ankyrin B antibody produced in mouse, clone S105-13, purified immunoglobulin,
Speziesreaktivität
human, mouse, rat
Anwendung
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-Ankyrin B - Atto 390 antibody produced in mouse, clone S105-13, purified immunoglobulin,
Speziesreaktivität
human, mouse, rat
Anwendung
immunocytochemistry
immunohistochemistry

western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human ANK2,
Spezies
human
MISSION® esiRNA, targeting mouse Ank2,
Spezies
mouse