Novel Small Molecule Inhibitors of Protein Kinase D Suppress NF-kappaB Activation and Attenuate the Severity of Rat Cerulein Pancreatitis.

Novel Small Molecule Inhibitors of Protein Kinase D Suppress NF-kappaB Activation and Attenuate the Severity of Rat Cerulein Pancreatitis.

Frontiers in physiology (2017-12-23)

Jingzhen Yuan, Tanya Tan, Meng Geng, Grace Tan, Chintan Chheda, Stephen J Pandol

RÉSUMÉ

Nuclear factor-kappa B (NF-κB) activation is a key early signal regulating inflammatory and cell death responses in acute pancreatitis. Our previous

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GF 109203X, synthetic, ≥90% (HPLC)

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