Metabolomic analysis shows differential hepatic effects of T

Metabolomic analysis shows differential hepatic effects of T

Scientific reports (2017-05-19)

Liliana F Iannucci, Federica Cioffi, Rosalba Senese, Fernando Goglia, Antonia Lanni, Paul M Yen, Rohit A Sinha

RÉSUMÉ

Nonalcoholic fatty liver disease (NAFLD) is a major health problem worldwide, and is often associated with lipotoxic injury, defective mitochondrial function, and insulin resistance. Thyroid hormones (THs) are important regulators of hepatic lipid metabolism. Among the THs, diiodothyronine (T

MATÉRIAUX

Référence du produit

Marque

Description du produit

C2978

Sigma-Aldrich

CelLytic^™ M, Cell Lysis Reagent, Suitable for Mammalian cell lysis and protein solubilization.

719536

Sigma-Aldrich

3,3′-Diiodo-L-thyronine (T2) hydrochloride, 98% (CP)