- Stereospecific Ni-catalyzed cross-coupling of potassium alkenyltrifluoroborates with alkyl halides.
Stereospecific Ni-catalyzed cross-coupling of potassium alkenyltrifluoroborates with alkyl halides.
Organic letters (2014-03-29)
Gary A Molander, O Andreea Argintaru
PMID24666316
RÉSUMÉ
A general method for the alkenylation of alkyl electrophiles using nearly stoichiometric amounts of the air- and moisture-stable potassium organotrifluoroborates has been developed. Various functional groups were tolerated on both the nucleophilic and electrophilic partner. Reactions of highly substituted E- and Z-alkenyltrifluoroborates, as well as vinyl- and propenyltrifluoroborates, were successful, and no loss of stereochemistry or regiochemistry was observed.
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Nickel de Raney®, W.R. Grace and Co. Raney® 2800, slurry, in H2O, active catalyst
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Nickel de Raney®, W.R. Grace and Co. Raney® 2400, slurry, in H2O, active catalyst
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Nickel, pellets, 100g, max. size 10mm, 99.999%
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Nickel, sputtering target, diam. × thickness 2.00 in. × 0.25 in., 99.95% trace metals basis
Nickel, foil, 100x100mm, thickness 1.6mm, 99%
Nickel, mesh, 100x250mm, nominal aperture 0.73mm, wire diameter 0.25mm, 26x26 wires/inch, open area 55%, plain weave mesh, 99%
Nickel, rod, 100mm, diameter 1.5mm, 99.99+%
Nickel, pellets, 100g, max. size 5mm, 99.99+%
Nickel, sphere, 100pcs, diameter 1.0mm, precision sphere grade 200, 99%
Nickel, foil, 100x100mm, thickness 0.25mm, annealed, 99%
Nickel, mesh, 30x30mm, nominal aperture 0.34mm, thickness 0.025mm, wire diameter 0.041mm, 70 wires/inch, open area 80%, electro-formed mesh, 99.9%
Nickel, foil, 50x50mm, thickness 0.3mm, as rolled, 99.999%
Nickel, foil, 100x100mm, thickness 0.1mm, annealed, 99%
Nickel, foil, 50x50mm, thickness 1.6mm, 99%
Nickel, wire reel, 100m, diameter 0.025mm, as drawn, 99.98%
Nickel, pellets, 20g, max. size 5mm, 99.99+%