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Intercalation and controlled release of pharmaceutically active compounds from a layered double hydroxide.

Chemical communications (Cambridge, England) (2002-09-21)
A I Khan, L Lei, A J Norquist, D O'Hare
RÉSUMÉ

A series of pharmaceutically active compounds including diclofenac, gemfibrozil, ibuprofen, naproxen, 2-propylpentanoic acid, 4-biphenylacetic acid and tolfenamic acid can be reversibly intercalated into a layered double hydroxide, initial studies suggest that these materials may have application as the basis of a novel tuneable drug delivery system.

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4-Biphenylacetic acid, 98%