Peptide directed transmembrane transport and nuclear localization of Ru(II) polypyridyl complexes in mammalian cells.

Peptide directed transmembrane transport and nuclear localization of Ru(II) polypyridyl complexes in mammalian cells.

Chemical communications (Cambridge, England) (2013-02-26)

Lorraine Blackmore, Roisin Moriarty, Ciaran Dolan, Kellie Adamson, Robert J Forster, Marc Devocelle, Tia E Keyes

RÉSUMÉ

The targeted delivery of luminescent Ru(II) polypyridyl complexes to the nucleus of live mammalian cells by a Nuclear Localisation Signal (NLS) peptide; NF-κB is demonstrated.

MATÉRIAUX

Référence du produit

Marque

Description du produit

545023

Sigma-Aldrich

Ruthenium, powder

326712

Sigma-Aldrich

Ruthenium black

209694

Sigma-Aldrich

Ruthenium, powder, −200 mesh, 99.9% trace metals basis