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Targeting ketone drugs towards transport by the intestinal peptide transporter, PepT1.

Organic & biomolecular chemistry (2009-03-06)
David Foley, Patrick Bailey, Myrtani Pieri, David Meredith
PMID19262922
RÉSUMÉ

Thiodipeptide prodrugs of the ketone nabumetone are shown to have affinity for, and be transported by, PepT1 in vitro.

MATÉRIAUX
Référence du produit
Marque
Description du produit
N6142
Supelco
Nabumetone, analytical standard
N0020000
Nabumetone, European Pharmacopoeia (EP) Reference Standard