- Synthesis of indoleamine 2,3-dioxygenase inhibitory analogues of the sponge alkaloid exiguamine A.
Synthesis of indoleamine 2,3-dioxygenase inhibitory analogues of the sponge alkaloid exiguamine A.
Journal of medicinal chemistry (2008-04-09)
Gavin Carr, Marco K W Chung, A Grant Mauk, Raymond J Andersen
PMID18393489
RÉSUMÉ
Synthetic analogues of the sponge natural product exiguamine A (3) have been prepared and evaluated for their ability to inhibit indoleamine 2,3-dioxygenase in vitro.