SMB01065

Neolicuroside

≥85% (LC/MS-ELSD)

• Synonyme(s) : 4-O-(beta-D-apiofuranosyl(1-2)-beta-D-glucopyranosyl)isoliquiritigenin, Isoliquiritigenin-4′-O-apiosyl(1→2)glucoside, Isoliquiritin apioside
• Formule empirique (notation de Hill): C₂₆H₃₀O₁₃
• Numéro CAS: 120926-46-7
• Poids moléculaire : 550.51
• Numéro MDL: MFCD20487832
• Code UNSPSC : 12352205
• Nomenclature NACRES : NA.25

Propriétés

• Source biologique: plant
• Pureté: ≥85% (LC/MS-ELSD)
• Forme: solid
• Poids mol.: 550.51
• Solubilité: water: slightly soluble
• Application(s): metabolomics; vitamins, nutraceuticals, and natural products
• Température de stockage: −20°C
• InChI: 1S/C26H30O13/c27-10-19-20(32)21(33)22(39-25-23(34)26(35,11-28)12-36-25)24(38-19)37-15-5-1-13(2-6-15)3-8-17(30)16-7-4-14(29)9-18(16)31/h1-9,19-25,27-29,31-35H,10-12H2/b8-3+/t19-,20-,21+,22-,23+,24-,25+,26-/m1/s1
• Clé InChI: VMMVZVPAYFZNBM-KVFWHIKKSA-N

Description

Description générale

Neolicuroside, also known as Isoliquiritin apioside, is a chalcone glycoside structurally related to steroidal saponins. This bioactive plant metabolite is commonly derived from the roots of Glycyrrhiza Sp. plants and has demonstrated anti-inflammatory, anti-tussive, anti-tumor, antigenotoxic(1), anti-diabetic, and antioxidant properties.

Natural product derived from plant source.

Application

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Actions biochimiques/physiologiques

Neolicuroside modulates signaling pathways (e.g., MAPK, NF-κB), impacting vital cell processes such as proliferation, differentiation, and apoptosis. Its multitargeted mechanism includes scavenging free radicals, suppressing pro-inflammatory cytokine production, inhibiting matrix metalloproteinase (MMP) activity and hindering cancer cell growth through apoptosis and cell cycle arrest. Furthermore, it also exerts immunomodulatory effects possibly by activating toll-like receptor 4 (TLR4).

Caractéristiques et avantages

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Autres remarques

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Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable