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Key Documents

RAB0017

Sigma-Aldrich

Human ANGPTL4 ELISA Kit

for serum, plasma and cell culture supernatants

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About This Item

Code UNSPSC :
41116158
Nomenclature NACRES :
NA.32

Espèces réactives

human

Conditionnement

kit of 96 wells (12 strips x 8 wells)

Technique(s)

ELISA: suitable
capture ELISA: suitable

Entrée

sample type cell culture supernatant(s)
sample type serum
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 20 pg/mL
standard curve range: 27.4-20000 pg/mL

Méthode de détection

colorimetric

Conditions d'expédition

wet ice

Température de stockage

−20°C

Informations sur le gène

human ... ANGPTL4(51378)

Description générale

The Human ANGPTL4 (Angiopoietin-like 4) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human ANGPTL4 in serum, plasma and cell culture supernatants.

Immunogène

Recombinant Human Angiopoietin-like 4

Application

For research use only. Not for use in diagnostic procedures.
Human angiopoietin-like protein 4 (ANGPTL4) ELISA kit has been used for the quantitative measurement of ANGPTL4 in serum and urinary samples.

Actions biochimiques/physiologiques

Angiopoietin like 4 (ANGPTL4) possesses a characteristic large fibrinogen/angiopoietin like domain. It inhibits lipoprotein lipase and thus increases plasma triglyceride levels. The protein regulates the uptake of free fatty acids in fasting and fed conditions. ANGPTL4 is also involved in homeostasis, insulin sensitivity and apoptosis of vascular endothelial cells. It has been reported to have a role in atherosclerosis and may modulate inflammatory responses.

Autres remarques

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

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  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)FDS
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  • RABWASH420X Wash Buffer (Item B)FDS

Pictogrammes

Corrosion
GHS05

Mention d'avertissement

Warning

Mentions de danger

H290

Conseils de prudence

P234 - P390

Classification des risques

Met. Corr. 1

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Serum angiopoietin-like 4 is over-expressed in COPD patients: association with pulmonary function and inflammation.
Wu YQ
European Review for Medical and Pharmacological Sciences (2016)
Viktoria Gusarova et al.
Nature communications, 9(1), 2252-2252 (2018-06-15)
Angiopoietin-like 4 (ANGPTL4) is an endogenous inhibitor of lipoprotein lipase that modulates lipid levels, coronary atherosclerosis risk, and nutrient partitioning. We hypothesize that loss of ANGPTL4 function might improve glucose homeostasis and decrease risk of type 2 diabetes (T2D). We
Angiopoietin-like protein 4 serum levels and gene polymorphisms are associated with large artery atherosclerotic stroke.
He XW
Journal of the Neurological Sciences (2016)
ANGPTL4 variants E40K and T266M are associated with lower fasting triglyceride levels and predicts cardiovascular disease risk in Type 2 diabetic Tunisian population.
Abid K
Lipids in Health and Disease (2016)
Angiopoietin-Like Protein 4 and Postprandial Skeletal Muscle Lipid Metabolism in Overweight and Obese Prediabetics.
van der Kolk BW
The Journal of Clinical Endocrinology and Metabolism (2016)
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