77626

N-tert-butyldiméthylsilyl-N-méthyltrifluoroacétamide

for GC derivatization, LiChropur^™, ≥98.0% (GC)

• Synonyme(s) : MTBSTFA
• Formule linéaire : CF₃CON(CH₃)Si(CH₃)₂C(CH₃)₃
• Numéro CAS: 77377-52-7
• Poids moléculaire : 241.33
• Numéro Beilstein : 3606546
• Numéro MDL: MFCD00009671
• Code UNSPSC : 12352111
• Nomenclature NACRES : NA.22

Propriétés

• Qualité: for GC derivatization; LiChropur^™
• Pureté: ≥98.0% (GC)
• Forme: liquid
• Pertinence de la réaction: reagent type: derivatization reagent; reaction type: Silylations
• Technique(s): gas chromatography (GC): suitable
• Indice de réfraction: n20/D 1.402 (lit.)
• Point d'ébullition: 172-175 °C (lit.)
• Densité: 1.036 g/mL at 25 °C (lit.)
• Température de stockage: 2-8°C
• Chaîne SMILES: CN(C(=O)C(F)(F)F)[Si](C)(C)C(C)(C)C
• InChI: 1S/C9H18F3NOSi/c1-8(2,3)15(5,6)13(4)7(14)9(10,11)12/h1-6H3
• Clé InChI: QRKUHYFDBWGLHJ-UHFFFAOYSA-N

Description

Description générale

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide is a silylating reagent which replaces the active hydrogen with tert-Butyldimethylsilyl group. The tert-Butyldimethylsilyl derivatives are found to be more resistant to hydrolysis and stable compared to trimethylsilyl (TMS) derivatives. This reagent is suitable for GC-MS analysis since it produces mass spectra, which can be easily interpreted. It is widely used for the silylation of different alcohols, thiols, phenols, carboxylic acids, amines, and amides.

Application

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide may be used as a derivatizing reagent for the determination of methionine sulfoxide and methionine in blood plasma and chlorpyrifos, diazinon and their major metabolites in sludge and sludge-fertilized agricultural soils using gas-chromatography coupled to mass spectrometry technique.

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Informations légales

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS02
• Mention d'avertissement: Warning
• Mentions de danger: H226
• Conseils de prudence: P210 - P233 - P240 - P241 - P242 - P243
• Classification des risques: Flam. Liq. 3
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 113.0 °F - closed cup
• Point d'éclair (°C): 45 °C - closed cup