236600
C-Reactive Protein, Human Ascites
C - reactive protein, Human Ascites, CAS 9007-41-4, is a major acute-phase plasma protein that composed of five identical non-covalently linked subunits.
Synonyme(s) :
C-Reactive Protein, Human Ascites, CRP
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About This Item
Niveau de qualité
Forme
liquid
Fabricant/nom de marque
Calbiochem®
Conditions de stockage
OK to freeze
Solubilité
water: soluble
Conditions d'expédition
wet ice
Température de stockage
2-8°C
Description générale
M.W. 23,000 (monomer); 115,000 (pentamer).
Native C-reactive protein from human ascites. CRP is a major acute-phase plasma protein that is dramatically elevated in patients with acute-phase conditions. Composed of five identical noncovalently linked subunits. Exhibits Ca2+-dependent binding to a variety of substrates. Important in diagnosis of rheumatoid arthritis. Suitable for immunological studies. In purified states and in plasma the monomeric form (M.W. ~21 kDa) aggregates as a cyclic pentamer.
Native C-reactive protein from human ascites. Major acute-phase plasma protein that is dramatically elevated in patients with acute-phase conditions. Composed of five identical noncovalently linked subunits. Exhibits Ca2+-dependent binding to a variety of substrates. Important in the diagnosis of rheumatoid arthritis. Suitable for immunological studies. In purified states and in plasma the monomeric form (M.W. 21 kDa) aggregates as a cyclic pentamer.
Conditionnement
Please refer to vial label for lot-specific concentration.
Avertissement
Toxicity: Standard Handling (A)
Forme physique
In 150 mM NaCl, 20 mM Tris, 2 mM CaCl₂, 0.1% NaN₃, pH 7.5.
Notes préparatoires
Prepared from ascites that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Remarque sur l'analyse
Single band by SDS-PAGE
Autres remarques
Christner, R.B., and Mortensen, R.F. 1994. J. Biol. Chem. 269, 9760.
Informations légales
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
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Katrine Pilely et al.
Frontiers in immunology, 8, 1040-1040 (2017-09-14)
Inflammation is a part of the initial process leading to atherosclerosis and cholesterol crystals (CC), found in atherosclerotic plaques, which are known to induce complement activation. The pentraxins C-reactive protein (CRP), long pentraxin 3 (PTX3), and serum amyloid P component
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
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