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E-060

Supelco

17β-Estradiol solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Formule empirique (notation de Hill):
C18H24O2
Numéro CAS:
50-28-2
Poids moléculaire :
272.38
Numéro MDL:
MFCD00003693
Code UNSPSC :
41116107
ID de substance PubChem :
329798978

Qualité

certified reference material

Niveau de qualité

300

Forme

liquid

Caractéristiques

Snap-N-Spike®/Snap-N-Shoot®

Conditionnement

ampule of 1 mL

Fabricant/nom de marque

Cerilliant®

Concentration

1.0 mg/mL in acetonitrile

Technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Application(s)

clinical testing
clinical testing

Format

single component solution

Température de stockage

2-8°C

Chaîne SMILES 

CC12CCC3C(CCc4cc(O)ccc34)C1CCC2O

InChI

1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1

Clé InChI

VOXZDWNPVJITMN-ZBRFXRBCSA-N

Informations sur le gène

human ... ESR1(2099)

Catégories apparentées

Description générale

A Certified Spiking Solution® suitable for use as starting material in calibrators, controls, or linearity standards for a variety of LC/MS or GC/MS applications from endocrinology to clinical and diagnostic testing.

17β-Estradiol belongs to the group of endogenous endocrine disruptors that disturb thyroid activity and function. It is also a sex hormone prescribed under the trade names Vagifem®, Estring®, Evamist, Elestrin®, Estrace®, and Estrogel® as a treatment for hypoestrogenism.

Application

The Certified Reference Material (CRM) in solution can also be used as follows:
  • Electrochemical determination of 17β-Estradiol in river water samples using a reduced graphene oxide and a metal complex porphyrin-based sensor
  • Development of a fluorescence resonance energy transfer (FRET) based aptasensor to determine 17β-Estradiol in environmental water, urine, and milk samples
  • Analysis of milk product samples to estimate 17β-Estradiol by high-performance liquid chromatography (HPLC) coupled with fluorescence detection following its solid phase extraction using graphene/multi-walled carbon nanotubes (MWCNTs)
  • Solid phase extraction of 17β-estradiol and 17α-ethinylestradiol from tap water samples using magnetic graphene oxide (GO)/γ-Fe2O3 nanoparticles for their simultaneous quantification by high-performance liquid chromatography (HPLC) combined with fluorescence detector
  • Multi-residue analysis of 17β-estradiol and 17α-ethinylestradiol in commercial pharmaceutical formulation and urine samples using hanging mercury drop electrode and screen printed carbon electrode

Caractéristiques et avantages

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Elestrin is a registered trademark of Azur Pharma
Estrace is a registered trademark of Warner Chilcott Company, LLC
Estring is a registered trademark of Pfizer Health AB
Estrogel is a registered trademark of Ascend Therapeutics, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Vagifem is a registered trademark of Novo Nordisk A/S Corp.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

E-061

17β-Estradiol-D5 solution, 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

E-073

17β-Estradiol-2,3,4-13C3 solution, ampule of 1 mL, Cerilliant®

E-074

Estriol solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

E-075

Estrone solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

E-076

17α-Ethynylestradiol solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

H-126

16α-Hydroxyestrone, 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

E-117

17β-Estradiol-2,3,4-13C3 solution, 10 μg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

H-127

2-Hydroxyestrone solution, 100 μg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

Pictogrammes

FlameExclamation mark
GHS02,GHS07

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

35.6 °F - closed cup

Point d'éclair (°C)

2 °C - closed cup

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Hirotaka Ishii et al.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 13(4), 323-334 (2007-07-24)
It is believed that sex hormones are synthesized in the gonads and reach the brain via the blood circulation. In contrast with this view, the authors have demonstrated that sex hormones are also synthesized locally in the hippocampus and that
S Safe
Vitamins and hormones, 62, 231-252 (2001-05-11)
Estrogen receptor-alpha (ER alpha) is a ligand-activated transcription factor and a member of the nuclear receptor superfamily. The classic mechanism of ER alpha action is associated with estrogen-induced formation of a nuclear ER alpha homodimer, binding to 5'-regulatory estrogen response
Mark A Tarnopolsky
Medicine and science in sports and exercise, 40(4), 648-654 (2008-03-05)
Women oxidize more lipid and less carbohydrate and protein compared with men during endurance exercise. The increase in fat oxidation is associated with higher intramyocellular lipid content and use as well as greater adipocyte lipolysis. Glucose rates of appearance and
William Rosner et al.
The Journal of clinical endocrinology and metabolism, 98(4), 1376-1387 (2013-03-07)
The objective of the study was to evaluate the current state of clinical assays for estradiol in the context of their applications. The participants were appointed by the Council of The Endocrine Society and charged with attaining the objective using
Richard Piet et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(26), 10828-10839 (2013-06-28)
Circulating gonadal steroid hormones are thought to modulate a wide range of brain functions. However, the effects of steroid fluctuations through the ovarian cycle on the intrinsic properties of neurons are not well understood. We examined here whether gonadal steroids
Afficher tous les articles scientifiques apparentés

Articles

UHPLC Analysis of Conjugated Estrogens on Ascentis ® Express C18

Separation of Estriol 3-(β-D-glucuronide) sodium salt; β-Estradiol 3-(β-D-glucuronide) 17-sulfate dipotassium salt; Estriol 3-sulfate sodium salt; β-Estradiol 3,17-disulfate dipotassium salt, ≥95%; β-Estradiol 17-(β-D-glucuronide) sodium salt; β-Estradiol 3-(β-D-glucuronide) sodium salt; Estrone 3-(β-D-glucuronide) sodium salt; β-Estradiol 3-sulfate sodium salt, ≥93%; Estriol, ≥97%; Estrone 3-sulfate sodium salt, contains ~35% Tris as stabilizer; β-Estradiol, ≥98%; α-Estradiol, powder, ≥98% (TLC); Estrone, ≥99%

Contenu apparenté

UHPLC Analysis of Conjugated Estrogens on Titan™ C18

The Titan C18 column provided efficient and rapid resolution of thirteen related estrogenic compounds. Ultra Ultra high purity solvents provided robust operation.

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