QBD10275

MAL-dPEG^®₈-acid

>95% (HPLC)

• Synonyme(s) : Carboxy-PEG-maleimide, Carboxy-PEG₈-maleimide, MAL-PEG₄₀₀-acid, MAL-PEG₈-COOH, MAL-PEG₈-acid
• Formule empirique (notation de Hill): C₂₆H₄₄N₂O₁₃
• Poids moléculaire : 592.63
• Numéro MDL: MFCD13184956
• Code UNSPSC : 12352106
• Nomenclature NACRES : NA.22

Propriétés

• Pureté: >95% (HPLC)
• Forme: solid or viscous liquid
• Capacité de réaction: reaction type: Pegylations
• Architecture des polymères: shape: linear; functionality: heterobifunctional
• Conditions d'expédition: ambient
• Température de stockage: −20°C

Description

Caractéristiques et avantages

MAL-dPEG₈-acid is a monodisperse crosslinker that joins sulfhydryl groups to free amines through a single molecular weight polyethylene glycol (PEG) chain of discrete length. The linker is 34 atoms and 38.8 Å long. The maleimidopropyl moiety reacts with sulfhydryl groups via a Michael addition reaction. The propionic acid terminus of the molecule reacts directly with free amines using EDC or another carbodiimide to form amide bonds. Alternatively, activation of the propionic acid group with N-hydroxysuccinimide (NHS), 2,3,5,6-tetrafluorophenol (TFP), or some other acylating agent permits amide bond formation under mild, controlled conditions.

Informations légales

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681

dPEG is a registered trademark of Quanta BioDesign

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable