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Merck

TNK2

tyrosine kinase, non-receptor, 2

Synonymes:
ACK, ACK-1, ACK1, p21cdc42Hs
Espèce(s):
Human TNK2 (10188), Mouse Tnk2 (51789), Rat Tnk2 (303882), cow TNK2 (280710), sheep TNK2 (101122917), domestic guinea pig Tnk2 (100715920), naked mole-rat Tnk2 (101701156), chicken TNK2 (431014), dog TNK2 (488025), domestic cat TNK2 (101098817)
ID UniProtKB:
Q07912, Q6ZMQ0, Q8N6U7, Q96H59
ID du gène:
  • Human(10188) Summary: This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]
  • Mouse(51789) tyrosine kinase, non-receptor, 2
  • Rat(303882) tyrosine kinase, non-receptor, 2
  • cow(280710) tyrosine kinase, non-receptor, 2
  • sheep(101122917) tyrosine kinase, non-receptor, 2
  • domestic guinea pig(100715920) tyrosine kinase, non-receptor, 2
  • naked mole-rat(101701156) tyrosine kinase, non-receptor, 2
  • chicken(431014) tyrosine kinase, non-receptor, 2
  • dog(488025) tyrosine kinase, non-receptor, 2
  • domestic cat(101098817) tyrosine kinase, non-receptor, 2

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ELISA

Référence du produit
Description
Espèce(s)
RAB0933
Phosphotyrosine TNK2 / Activated CDC42 Kinase 1 ELISA Kit, ,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
HPA041954
Anti-TNK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
SAB4301243
Anti-phospho-ACK1 (pTyr284) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse
Application
immunohistochemistry
western blot
SAB5700422
Anti-Phospho-TNK2-Y284 antibody produced in rabbit, ,
Espèces réactives
human
Application
western blot
SAB1401511
Anti-TNK2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
immunofluorescence
western blot
GW21569B
Anti-TNK2 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human
Application
western blot

esiRNA

Référence du produit
Description
Espèce(s)
EHU063001
MISSION® esiRNA, targeting human TNK2,
Espèce(s)
human
EMU067591
MISSION® esiRNA, targeting mouse Tnk2,
Espèce(s)
mouse