Accéder au contenu
MilliporeSigma

TNFRSF11B

tumor necrosis factor receptor superfamily, member 11b

Synonymes:
OCIF, OPG, TR1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4982) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(18383) tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
  • Rat(25341) tumor necrosis factor receptor superfamily, member 11b
  • Zebrafish(407674) tumor necrosis factor receptor superfamily, member 11b
  • dog(482025) tumor necrosis factor receptor superfamily, member 11b
  • Horse(100065885) tumor necrosis factor receptor superfamily, member 11b
  • domestic cat(101096878) tumor necrosis factor receptor superfamily, member 11b
  • chicken(378803) tumor necrosis factor receptor superfamily, member 11b
  • domestic guinea pig(100715850) tumor necrosis factor receptor superfamily, member 11b
  • Domestic Rabbit(100348133) tumor necrosis factor receptor superfamily, member 11b
  • naked mole-rat(101709512) tumor necrosis factor receptor superfamily, member 11b
  • cow(523822) tumor necrosis factor receptor superfamily, member 11b
  • Goat(100860896) tumor necrosis factor receptor superfamily, member 11b

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Référence du produit
Description
Espèce(s)
Human Osteoprotegerin / TNFRSF11b ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Espèce(s)
human
Mouse Osteoprotegerin ELISA Kit, for serum, plasma, cell culture supernatant,
Espèce(s)
mouse
Porcine OPG ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Espèce(s)

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-Osteoprotegerin/TNFRSF11B Antibody, from rabbit, purified by affinity chromatography,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-Osteoprotegerin antibody produced in goat, affinity isolated antibody, lyophilized powder,
Espèces réactives
mouse
Application
immunohistochemistry
neutralization

western blot
Anti-TNFRSF11B antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-TR11B antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse
Application
ELISA
western blot
Anti-TNFRSF11B antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot

Proteins

Référence du produit
Description
Espèce(s)
Osteoprotegerin (OPG) human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Espèce(s)
human
Osteoprotegerin/Fc Chimera from mouse, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Espèce(s)
mouse

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human TNFRSF11B,
Espèce(s)
human