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MilliporeSigma

SUN2

Sad1 and UNC84 domain containing 2

Synonymes:
UNC84B
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(25777) Summary: SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]
  • Mouse(223697) Sad1 and UNC84 domain containing 2
  • Rat(315135) Sad1 and UNC84 domain containing 2
  • domestic guinea pig(100734538) Sad1 and UNC84 domain containing 2
  • naked mole-rat(101703115) Sad1 and UNC84 domain containing 2
  • cow(618392) Sad1 and UNC84 domain containing 2
  • sheep(101106156) Sad1 and UNC84 domain containing 2
  • Thale Cress(820242) SAD1/UNC-84 domain-containing protein 2
  • chicken(418021) Sad1 and UNC84 domain containing 2
  • dog(481250) Sad1 and UNC84 domain containing 2
  • domestic cat(101096079) Sad1 and UNC84 domain containing 2

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-SUN2 Antibody, clone 3.1E, clone 3.1E, from mouse,
Espèces réactives
human, mouse, rat
Application
immunocytochemistry
western blot
Anti-SUN2 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-SUN2 Antibody, from rabbit, purified by affinity chromatography,
Espèces réactives
human, mouse
Application
immunocytochemistry
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human SUN2,
Espèce(s)
human