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SOX2

SRY (sex determining region Y)-box 2

Synonymes:
ANOP3, MCOPS3
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(6657) Summary: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]
  • Mouse(20674) SRY-box containing gene 2
  • Rat(499593) SRY (sex determining region Y)-box 2
  • Zebrafish(378723) SRY-box containing gene 2
  • Horse(100146979) SRY (sex determining region Y)-box 2
  • domestic cat(100379629) SRY (sex determining region Y)-box 2
  • dog(488092) SRY (sex determining region Y)-box 2
  • chicken(396105) SRY (sex determining region Y)-box 2
  • cow(784383) SRY (sex determining region Y)-box 2
  • Goat(100861576) SRY (sex determining region Y)-box 2
  • sheep(101110563) SRY (sex determining region Y)-box 2
  • domestic guinea pig(100714747) SRY (sex determining region Y)-box 2
  • naked mole-rat(101723266) SRY (sex determining region Y)-box 2

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anticorps anti-Sox2, Chemicon®, from rabbit,
Espèces réactives
bovine, human, mouse, rat, rhesus macaque
Application
immunocytochemistry
immunofluorescence

immunohistochemistry

western blot
Anti-Sox-2 Antibody, clone 1A2, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, mouse
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-SOX2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
western blot
Monoclonal Anti-SOX2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL4716, purified immunoglobulin,
Espèces réactives
human, mouse
Application
immunofluorescence
immunohistochemistry

western blot
Anti-sox2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
zebrafish
Application
immunohistochemistry
western blot

Proteins

Référence du produit
Description
Espèce(s)
Sox2 human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Espèce(s)
human
Sox2 TAT human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human SOX2,
Espèce(s)
human