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MilliporeSigma

SIRT6

sirtuin 6

Synonymes:
SIR2L6
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(51548) Summary: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010]
  • Mouse(50721) sirtuin 6
  • Rat(299638) sirtuin 6
  • fruit fly(41254) CG6284 gene product from transcript CG6284-RB
  • Zebrafish(415161) sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae)
  • chicken(428332) sirtuin 6
  • domestic cat(101100540) sirtuin 6
  • dog(485045) sirtuin 6
  • cow(535416) sirtuin 6
  • sheep(101113327) sirtuin 6
  • naked mole-rat(101706114) sirtuin 6
  • domestic guinea pig(100734667) sirtuin 6

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-Sirt6 (C-terminal) antibody produced in rabbit, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human
Application
immunofluorescence
western blot
Anti-SIRT6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Monoclonal Anti-SIRT6 antibody produced in mouse, clone 1D8, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
Anti-SIRT6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-SIRT6 Antibody, clone 1D0L6, Rabbit Monoclonal, ,
Espèces réactives
human
Application
western blot

Proteins

Référence du produit
Description
Espèce(s)
Sirtuin 6 human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Espèce(s)
human
SIRT6, active, His tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Sirt6,
Espèce(s)
mouse
MISSION® esiRNA, targeting human SIRT6,
Espèce(s)
human