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SELPLG

selectin P ligand

Synonymes:
CD162, CLA, PSGL-1, PSGL1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(6404) Summary: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]
  • Mouse(20345) selectin, platelet (p-selectin) ligand
  • Rat(363930) selectin P ligand
  • cow(617434) selectin P ligand
  • sheep(101102589) selectin P ligand
  • naked mole-rat(101713908) selectin P ligand
  • domestic guinea pig(100712957) selectin P ligand
  • Zebrafish(100884146) selectin P ligand
  • chicken(772212) selectin P ligand
  • dog(611673) selectin P ligand
  • Horse(100034025) selectin P ligand
  • domestic cat(101087945) selectin P ligand

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ELISA

Référence du produit
Description
Espèce(s)
Human PSGL-1 ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-PSGL-1/CD162 Antibody, clone KPL-1 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human
Application
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-P-Selectin Glycoprotein Ligand-1 Antibody, clone KPL-1, clone KPL-1, Chemicon®, from mouse,
Espèces réactives
human
Application
flow cytometry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-PSGL-1/CD162 Antibody, clone HECA-452, ,
Espèces réactives
human
Application
flow cytometry
immunohistochemistry

western blot
Monoclonal Anti-CD162-APC antibody produced in mouse, clone TC2,
Espèces réactives
Application
flow cytometry
Anti-SELPLG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human SELPLG,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Selplg,
Espèce(s)
mouse