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RYK

receptor-like tyrosine kinase

Synonymes:
D3S3195, JTK5, JTK5A, RYK1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(6259) Summary: The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012]
  • Mouse(20187) receptor-like tyrosine kinase
  • Rat(140585) receptor-like tyrosine kinase
  • Zebrafish(558502) receptor-like tyrosine kinase
  • chicken(395409) receptor-like tyrosine kinase
  • domestic cat(101086838) receptor-like tyrosine kinase
  • dog(477074) receptor-like tyrosine kinase
  • cow(781353) receptor-like tyrosine kinase
  • sheep(101114583) receptor-like tyrosine kinase
  • domestic guinea pig(100727608) receptor-like tyrosine kinase
  • naked mole-rat(101722098) receptor-like tyrosine kinase
  • Domestic Rabbit(100008628) receptor-like tyrosine kinase

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ELISA

Référence du produit
Description
Espèce(s)
Phosphotyrosine RYK ELISA Kit, ,
Espèce(s)
human
Human Ryk ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-RYK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-RYK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-RYK antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-RYK (C-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunohistochemistry

western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human RYK,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Ryk,
Espèce(s)
mouse