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ROCK2

Rho-associated, coiled-coil containing protein kinase 2

Synonymes:
ROCK-II
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(9475) Summary: The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008]
  • Mouse(19878) Rho-associated coiled-coil containing protein kinase 2
  • Rat(25537) Rho-associated coiled-coil containing protein kinase 2
  • chicken(374182) Rho-associated, coiled-coil containing protein kinase 2
  • dog(482970) Rho-associated, coiled-coil containing protein kinase 2
  • domestic cat(101094501) Rho-associated, coiled-coil containing protein kinase 2
  • cow(282041) Rho-associated, coiled-coil containing protein kinase 2
  • sheep(101103800) Rho-associated, coiled-coil containing protein kinase 2
  • sheep(100294663) Rho-associated, coiled-coil containing protein kinase 2
  • naked mole-rat(101724195) Rho-associated, coiled-coil containing protein kinase 2
  • domestic guinea pig(100713798) Rho-associated, coiled-coil containing protein kinase 2

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-ROCK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-ROCK2 Antibody, clone 1B20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
canine, feline, horse, human, monkey, mouse, rat
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-phospho-ROCK2 (pTyr722) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
western blot
Anti-ROKα/ROCK-II Antibody, clone A9W4, rabbit monoclonal, culture supernatant, clone A9W4, from rabbit,
Espèces réactives
bovine, human, mouse, rat
Application
immunoprecipitation (IP)
western blot
Anti-ROCK2 Antibody, clone 8G3U2, Rabbit Monoclonal, ,
Espèces réactives
human, rat
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
Y-27632 dihydrochloride, ≥98% (HPLC),
Espèce(s)
human
Adénine, ≥99%,
Espèce(s)
human, rat, mouse
Adénine, BioReagent, suitable for cell culture,
Espèce(s)
human, rat, mouse
Adénine, BioReagent, suitable for plant cell culture, ≥99%,
Espèce(s)
human, rat, mouse

Proteins

Référence du produit
Description
Espèce(s)
ROCK2 (5-554), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human ROCK2,
Espèce(s)
human