RNASEH2A
ribonuclease H2, subunit A
Synonymes:
AGS4, JUNB, RNASEHI, RNHIA, RNHL
Espèce(s):
Human RNASEH2A (10535), Mouse Rnaseh2a (69724), Rat Rnaseh2a (364974), Zebrafish rnaseh2a (393195), domestic cat RNASEH2A (101086121), dog RNASEH2A (484925), cow RNASEH2A (512830), sheep RNASEH2A (101105746), Goat RNASEH2A (100860936), domestic guinea pig Rnaseh2a (100715505)
ID UniProtKB:
ID du gène:
- Human(10535) Summary: The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009]
- Mouse(69724) ribonuclease H2, large subunit
- Rat(364974) ribonuclease H2, subunit A
- Zebrafish(393195) ribonuclease H2, subunit A
- domestic cat(101086121) ribonuclease H2, subunit A
- dog(484925) ribonuclease H2, subunit A
- cow(512830) ribonuclease H2, subunit A
- sheep(101105746) ribonuclease H2, subunit A
- Goat(100860936) ribonuclease H2, subunit A
- domestic guinea pig(100715505) ribonuclease H2, subunit A
- naked mole-rat(101714999) ribonuclease H2, subunit A
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-RNASEH2A antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
immunohistochemistry
western blot
western blot
Anti-RNASEH2A antibody produced in rabbit, IgG fraction of antiserum,
Espèces réactives
bovine, goat, horse, human, pig
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-RNASEH2A antibody produced in mouse, clone 3G5-F5, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot
western blot
Anti-RNASEH2A antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
immunofluorescence
western blot
western blot
Anti-RNASEH2A antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot