PLS3
plastin 3
- Human(5358) Summary: Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
- Mouse(102866) plastin 3 (T-isoform)
- Rat(81748) plastin 3
- Zebrafish(436598) plastin 3 (T isoform)
- chicken(422222) plastin 3
- dog(481025) plastin 3
- Horse(100053927) plastin 3
- domestic cat(101100793) plastin 3
- domestic guinea pig(100718763) plastin 3
- naked mole-rat(101724466) plastin 3
- cow(505687) plastin 3
- sheep(101107418) plastin 3
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