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PARP1

poly (ADP-ribose) polymerase 1

Synonymes:
ADPRT, ADPRT 1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(142) Summary: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(11545) poly (ADP-ribose) polymerase family, member 1
  • Rat(25591) poly (ADP-ribose) polymerase 1
  • Thale Cress(817690) poly [ADP-ribose] polymerase 2
  • Zebrafish(560788) poly (ADP-ribose) polymerase family, member 1
  • chicken(396199) poly (ADP-ribose) polymerase 1
  • dog(490385) poly (ADP-ribose) polymerase 1
  • domestic cat(101081434) poly (ADP-ribose) polymerase 1
  • Horse(100058523) poly (ADP-ribose) polymerase 1
  • cow(286764) poly (ADP-ribose) polymerase 1
  • domestic guinea pig(100733925) poly (ADP-ribose) polymerase 1
  • naked mole-rat(101703207) poly (ADP-ribose) polymerase 1
  • sheep(100135697) poly (ADP-ribose) polymerase 1

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-PARP (Cleaved-Asp214) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse
Application
ELISA
western blot
Anticorps anti-poly(ADP-ribose), clone 10H, clone 10H, from mouse,
Espèces réactives
human
Application
immunofluorescence
immunoprecipitation (IP)

western blot
Anti-PARP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-PARP1 antibody produced in mouse, clone 3G4, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence

western blot
Anti-cleaved PARP-1 Antibody, clone 2G13 Antibody, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, monkey
Application
flow cytometry
immunocytochemistry

immunohistochemistry

western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
Benzamide, 99%,
Espèce(s)
human
3-Aminobenzamide, ≥99% (TLC),
Espèce(s)
mouse
Benzamide, purified by sublimation, ≥99.5%,
Espèce(s)
human
6-(5H)-Phenanthridinone, technical grade,
Espèce(s)
human
Nicotinamide, BioReagent, suitable for cell culture, suitable for insect cell culture,
Espèce(s)
human

Proteins

Référence du produit
Description
Espèce(s)
PARP-1 human, recombinant, expressed in E. coli,
Espèce(s)
human
PARP1 Active human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
Espèce(s)
human
Monoclonal Anti-PARP1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2220, purified immunoglobulin, buffered aqueous glycerol solution,
Espèce(s)
human
Monoclonal Anti-PARP1, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2209, purified immunoglobulin, buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human PARP1,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Parp1,
Espèce(s)
mouse