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OGG1

8-oxoguanine DNA glycosylase

Synonymes:
HMMH, HOGG1, MUTM, OGH1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4968) Summary: This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008]
  • Mouse(18294) 8-oxoguanine DNA-glycosylase 1
  • Rat(81528) 8-oxoguanine DNA glycosylase
  • fruit fly(31806) CG1795 gene product from transcript CG1795-RA
  • cow(520497) 8-oxoguanine DNA glycosylase
  • domestic cat(101091094) 8-oxoguanine DNA glycosylase
  • dog(484666) 8-oxoguanine DNA glycosylase
  • chicken(771001) 8-oxoguanine DNA glycosylase
  • Thale Cress(838775) 8-oxoguanine-DNA glycosylase 1
  • Zebrafish(791194) 8-oxoguanine DNA glycosylase
  • sheep(101104015) 8-oxoguanine DNA glycosylase
  • naked mole-rat(101697522) 8-oxoguanine DNA glycosylase
  • domestic guinea pig(100731436) 8-oxoguanine DNA glycosylase

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anticorps anti-8-oxoguanine, clone 483.15, ascites fluid, clone 483.15, Chemicon®,
Espèces réactives
human, monkey, mouse, primate, rat
Application
ChIP
ELISA

immunocytochemistry
Anti-8-Oxoguanine, clone 483.15 Antibody (Ascites Free), clone 483.15, from mouse,
Espèces réactives
all, bovine, human, monkey, mouse, rat
Application
ELISA
immunocytochemistry

immunohistochemistry
Anti-OGG1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-OGG1 Antibody, from rabbit, purified by affinity chromatography,
Espèces réactives
human
Application
western blot
Anti-OGG1 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human OGG1,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Ogg1,
Espèce(s)
mouse