OGG1
8-oxoguanine DNA glycosylase
Synonymes:
HMMH, HOGG1, MUTM, OGH1
Espèce(s):
Human OGG1 (4968), Mouse Ogg1 (18294), Rat Ogg1 (81528), fruit fly Ogg1 (31806), cow OGG1 (520497), domestic cat OGG1 (101091094), dog OGG1 (484666), chicken OGG1 (771001), Thale Cress OGG1 (838775), Zebrafish ogg1 (791194) ...Plus
ID UniProtKB:
ID du gène:
- Human(4968) Summary: This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008]
- Mouse(18294) 8-oxoguanine DNA-glycosylase 1
- Rat(81528) 8-oxoguanine DNA glycosylase
- fruit fly(31806) CG1795 gene product from transcript CG1795-RA
- cow(520497) 8-oxoguanine DNA glycosylase
- domestic cat(101091094) 8-oxoguanine DNA glycosylase
- dog(484666) 8-oxoguanine DNA glycosylase
- chicken(771001) 8-oxoguanine DNA glycosylase
- Thale Cress(838775) 8-oxoguanine-DNA glycosylase 1
- Zebrafish(791194) 8-oxoguanine DNA glycosylase
- sheep(101104015) 8-oxoguanine DNA glycosylase
- naked mole-rat(101697522) 8-oxoguanine DNA glycosylase
- domestic guinea pig(100731436) 8-oxoguanine DNA glycosylase
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anticorps anti-8-oxoguanine, clone 483.15, ascites fluid, clone 483.15, Chemicon®,
Espèces réactives
human, monkey, mouse, primate, rat
Application
ChIP
ELISA
immunocytochemistry
ELISA
immunocytochemistry
Anti-8-Oxoguanine, clone 483.15 Antibody (Ascites Free), clone 483.15, from mouse,
Espèces réactives
all, bovine, human, monkey, mouse, rat
Application
ELISA
immunocytochemistry
immunohistochemistry
immunocytochemistry
immunohistochemistry
Anti-OGG1 Antibody, from rabbit, purified by affinity chromatography,
Espèces réactives
human
Application
western blot
Anti-OGG1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-OGG1 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
western blot