NDUFV1
NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
- Human(4723) Summary: The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009]
- Mouse(17995) NADH dehydrogenase (ubiquinone) flavoprotein 1
- Rat(293655) NADH dehydrogenase (ubiquinone) flavoprotein 1
- Zebrafish(445291) NADH dehydrogenase (ubiquinone) flavoprotein 1
- chicken(430210) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
- dog(476004) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
- cow(287014) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
- domestic cat(101093395) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
- sheep(101121129) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
- naked mole-rat(101726275) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
- domestic guinea pig(100725831) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
western blot