NDUFS4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
AQDQ, CI-18
Human NDUFS4 (4724), Mouse Ndufs4 (17993), Rat Ndufs4 (499529), naked mole-rat Ndufs4 (101699557), sheep NDUFS4 (101118899), Zebrafish ndufs4 (573689), cow NDUFS4 (327680), domestic cat NDUFS4 (101089240), dog NDUFS4 (479335), chicken NDUFS4 (374122)
- Human(4724) Summary: This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes. [provided by RefSeq, Jul 2008]
- Mouse(17993) NADH dehydrogenase (ubiquinone) Fe-S protein 4
- Rat(499529) NADH dehydrogenase (ubiquinone) Fe-S protein 4
- naked mole-rat(101699557) NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
- sheep(101118899) NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
- Zebrafish(573689) NADH dehydrogenase (ubiquinone) Fe-S protein 4, (NADH-coenzyme Q reductase)
- cow(327680) NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
- domestic cat(101089240) NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
- dog(479335) NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
- chicken(374122) NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
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Antibodies
Anti-NDUFS4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human, mouse, rat
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-NDUFS4, (C-terminal) antibody produced in mouse, clone 1A1, ascites fluid,
human
ELISA
western blot
western blot
Monoclonal Anti-NDUFS4 antibody produced in mouse, clone 1A1, purified immunoglobulin, buffered aqueous solution,
human, mouse, rat
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-NDUFS4 antibody produced in mouse, clone 3A4, ascites fluid, solution,
human
ELISA
Small Molecule - Inhibitor
Metformin hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
human
Metformin hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
human