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NDUFS4

NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)

Synonymes:
AQDQ, CI-18
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4724) Summary: This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes. [provided by RefSeq, Jul 2008]
  • Mouse(17993) NADH dehydrogenase (ubiquinone) Fe-S protein 4
  • Rat(499529) NADH dehydrogenase (ubiquinone) Fe-S protein 4
  • naked mole-rat(101699557) NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
  • sheep(101118899) NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
  • Zebrafish(573689) NADH dehydrogenase (ubiquinone) Fe-S protein 4, (NADH-coenzyme Q reductase)
  • cow(327680) NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
  • domestic cat(101089240) NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
  • dog(479335) NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
  • chicken(374122) NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-NDUFS4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-NDUFS4, (C-terminal) antibody produced in mouse, clone 1A1, ascites fluid,
Espèces réactives
human
Application
ELISA
western blot
Monoclonal Anti-NDUFS4 antibody produced in mouse, clone 1A1, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Monoclonal Anti-NDUFS4 antibody produced in mouse, clone 3A4, ascites fluid, solution,
Espèces réactives
human
Application
ELISA
Anti-NDUFS4 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
Metformin hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
1,1-Dimethylbiguanide hydrochloride, 97%,
Espèce(s)
human
Metformin hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human
Metformin hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Metformin hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Ndufs4,
Espèce(s)
mouse
MISSION® esiRNA, targeting human NDUFS4,
Espèce(s)
human