MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
Synonymes:
MAPKKK1, MEKK, MEKK 1, MEKK1, SRXY6
Espèce(s):
Human MAP3K1 (4214), Mouse Map3k1 (26401), Rat Map3k1 (116667), sheep MAP3K1 (101112260), domestic guinea pig Map3k1 (100723456), naked mole-rat Map3k1 (101720769), Domestic Rabbit MAP3K1 (100328655), Zebrafish map3k1 (100334486), chicken MAP3K1 (427144), cow MAP3K1 (523962) ...Plus
ID UniProtKB:
ID du gène:
- Human(4214) Summary: The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. [provided by RefSeq, Mar 2012]
- Mouse(26401) mitogen-activated protein kinase kinase kinase 1
- Rat(116667) mitogen activated protein kinase kinase kinase 1
- sheep(101112260) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
- domestic guinea pig(100723456) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
- naked mole-rat(101720769) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
- Domestic Rabbit(100328655) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
- Zebrafish(100334486) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
- chicken(427144) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
- cow(523962) mitogen-activated protein kinase kinase kinase 1
- Horse(100061688) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
- domestic cat(101090328) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
- dog(478061) mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-MAP3K1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Monoclonal Anti-MAP3K1 antibody produced in mouse, clone 2F6, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
proximity ligation assay
western blot
proximity ligation assay
western blot
Anti-phospho-MAP3K1 (pThr1402) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MAP3K1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-MEKKK 1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse
Application
ELISA
western blot
western blot
Small Molecule - Inhibitor
Proteins
Référence du produit
Description
Espèce(s)
MEKK1 (664-1512), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human