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LGI1

leucine-rich, glioma inactivated 1

Synonymes:
ADLTE, ADPAEF, ADPEAF, EPITEMPIN, EPT, ETL1, IB1099
Espèce(s):
Human LGI1 (9211), Mouse Lgi1 (56839), Rat Lgi1 (252892), sheep LGI1 (101105294), Domestic Rabbit LGI1 (100344253), domestic guinea pig Lgi1 (100726518), naked mole-rat Lgi1 (101703526), chicken LGI1 (423802), cow LGI1 (617080), domestic cat LGI1 (101088030)
ID UniProtKB:
O95970, A8K0Z1, B4E1S0, Q5W001, Q5W002, Q8NI23, Q96LF5
ID du gène:
  • Human(9211) Summary: This gene is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobic segment representing a putative transmembrane domain with the amino terminus located outside the cell. It also contains leucine-rich repeats with conserved cysteine-rich flanking sequences. This gene is predominantly expressed in neural tissues and its expression is reduced in low grade brain tumors and significantly reduced or absent in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. [provided by RefSeq, Jul 2008]
  • Mouse(56839) leucine-rich repeat LGI family, member 1
  • Rat(252892) leucine-rich, glioma inactivated 1
  • sheep(101105294) leucine-rich, glioma inactivated 1
  • Domestic Rabbit(100344253) leucine-rich, glioma inactivated 1
  • domestic guinea pig(100726518) leucine-rich, glioma inactivated 1
  • naked mole-rat(101703526) leucine-rich, glioma inactivated 1
  • chicken(423802) leucine-rich, glioma inactivated 1
  • cow(617080) leucine-rich, glioma inactivated 1
  • domestic cat(101088030) leucine-rich, glioma inactivated 1
  • dog(477777) leucine-rich, glioma inactivated 1

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Antibodies

Product Number
Description
Espèces réactives
Application
PRS4489
Anti-LGI1 (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB1406794
Anti-LGI1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
SAB5201438
Monoclonal Anti-Lgi1 - Apc antibody produced in mouse, clone S283-7, purified immunoglobulin,
Espèces réactives
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot
SAB5201440
Monoclonal Anti-Lgi1 - Fitc antibody produced in mouse, clone S283-7, purified immunoglobulin,
Espèces réactives
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot
SAB5201441
Monoclonal Anti-Lgi1 - Hrp antibody produced in mouse, clone S283-7, purified immunoglobulin,
Espèces réactives
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot

esiRNA

Product Number
Description
Espèce(s)
EHU142771
MISSION® esiRNA, targeting human LGI1,
Espèce(s)
human
EMU057941
MISSION® esiRNA, targeting mouse Lgi1,
Espèce(s)
mouse