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ITGAM

integrin, alpha M (complement component 3 receptor 3 subunit)

Synonymes:
CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(3684) Summary: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • Mouse(16409) integrin alpha M
  • Rat(25021) integrin, alpha M
  • Horse(100064803) integrin, alpha M (complement component 3 receptor 3 subunit)
  • cow(407124) integrin, alpha M (complement component 3 receptor 3 subunit)
  • domestic cat(101087957) integrin, alpha M (complement component 3 receptor 3 subunit)
  • dog(489928) integrin, alpha M (complement component 3 receptor 3 subunit)
  • domestic guinea pig(100135561) integrin, alpha M (complement component 3 receptor 3 subunit)
  • naked mole-rat(101719288) integrin, alpha M (complement component 3 receptor 3 subunit)
  • sheep(443217) integrin, alpha M (complement component 3 receptor 3 subunit)
  • Domestic Rabbit(100351865) integrin, alpha M (complement component 3 receptor 3 subunit)

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ELISA

Référence du produit
Description
Espèce(s)
Human Integrin alpha-M ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-Integrin αM [CD11b] Antibody, clone OX-42, clone OX-42, Chemicon®, from mouse,
Espèces réactives
rat
Application
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
®, clone 2LPM19c, Milli-Mark®, from mouse,
Espèces réactives
human
Application
flow cytometry
Anti-CD11b/CD18 Antibody, clone mAb107, clone mAb107, from mouse,
Espèces réactives
human, nonhuman primates
Application
dot blot
flow cytometry

immunohistochemistry

inhibition assay
Anti-CD11B antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-CD11b Antibody, clone 2K14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human
Application
flow cytometry
immunocytochemistry

immunohistochemistry

western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human ITGAM,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Itgam,
Espèce(s)
mouse