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IL18BP

interleukin 18 binding protein

Synonymes:
IL18BPa
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(10068) Summary: The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
  • Mouse(16068) interleukin 18 binding protein
  • Rat(84388) interleukin 18 binding protein
  • domestic guinea pig(100714819) interleukin 18 binding protein
  • naked mole-rat(101721919) interleukin 18 binding protein
  • sheep(101118983) interleukin 18 binding protein
  • cow(617470) interleukin 18 binding protein
  • domestic cat(101096599) interleukin 18 binding protein
  • dog(476818) interleukin 18 binding protein

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ELISA

Référence du produit
Description
Espèce(s)
Human IL-18 BPa  ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Monoclonal Anti-IL18BP antibody produced in mouse, clone 2A9, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
western blot
Anti-IL18BP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-IL18BP antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
western blot

Proteins

Référence du produit
Description
Espèce(s)
IL18BP human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human IL18BP,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Il18bp,
Espèce(s)
mouse