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HHIP

hedgehog interacting protein

Synonymes:
HIP
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(64399) Summary: This gene encodes a member of the hedgehog-interacting protein (HHIP) family. The hedgehog (HH) proteins are evolutionarily conserved protein, which are important morphogens for a wide range of developmental processes, including anteroposterior patterns of limbs and regulation of left-right asymmetry in embryonic development. Multiple cell-surface receptors are responsible for transducing and/or regulating HH signals. The HHIP encoded by this gene is a highly conserved, vertebrate-specific inhibitor of HH signaling. It interacts with all three HH family members, SHH, IHH and DHH. Two single nucleotide polymorphisms (SNPs) near this gene are significantly associated with risk of chronic obstructive pulmonary disease (COPD). A single nucleotide polymorphism in this gene is also strongly associated with human height.[provided by RefSeq, Feb 2011]
  • Mouse(15245) Hedgehog-interacting protein
  • Rat(291936) Hedgehog-interacting protein
  • sheep(101111396) hedgehog interacting protein
  • Domestic Rabbit(100344588) hedgehog interacting protein
  • domestic guinea pig(100728644) hedgehog interacting protein
  • naked mole-rat(101724427) hedgehog interacting protein
  • Zebrafish(326102) hedgehog interacting protein
  • domestic cat(101087058) hedgehog interacting protein
  • cow(540830) hedgehog interacting protein
  • Horse(100062868) hedgehog interacting protein
  • dog(475452) hedgehog interacting protein
  • chicken(422460) hedgehog interacting protein

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Monoclonal Anti-HHIP antibody produced in mouse, clone 5D11, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-HHIP antibody produced in rabbit, ,
Espèces réactives
chicken, human, mouse
Application
immunocytochemistry
immunofluorescence

immunohistochemistry

western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Hhip,
Espèce(s)
mouse