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Merck

FSCN1

fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)

Synonymes:
FAN1, HSN, SNL, p55
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(6624) Summary: This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]
  • Mouse(14086) fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)
  • Rat(683788) fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)
  • chicken(416485) fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
  • dog(489880) fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
  • cow(507342) fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
  • domestic cat(101098761) fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
  • domestic guinea pig(100733694) fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
  • naked mole-rat(101716557) fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
  • sheep(101108186) fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-FSCN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Fascin (55k-2) Mouse Monoclonal Antibody, ,
Espèces réactives
human
Application
immunohistochemistry
Anti-Fascin/FSCN1 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-Fascin Antibody, clone 55K2, clone 55K2, Chemicon®, from mouse,
Espèces réactives
echinoderm, gerbil, human, mammals, sea urchin
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-FSCN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunohistochemistry

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Fscn1,
Espèce(s)
mouse
MISSION® esiRNA, targeting human FSCN1,
Espèce(s)
human