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DAXX

death-domain associated protein

Synonymes:
BING2, DAP6, EAP1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(1616) Summary: This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]
  • Mouse(13163) Fas death domain-associated protein
  • Rat(140926) death-domain associated protein
  • naked mole-rat(101717412) death-domain associated protein
  • domestic guinea pig(100730008) death-domain associated protein
  • sheep(100505403) death-domain associated protein
  • Zebrafish(561006) death-associated protein 6
  • dog(474873) death-domain associated protein
  • cow(504336) death-domain associated protein
  • domestic cat(101089265) death-domain associated protein

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-DAXX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Monoclonal Anti-DAXX antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL3580, purified immunoglobulin, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
Anti-DAXX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
Anti-DAXX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Rabbit anti-DAXX Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Espèces réactives
human
Application
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Daxx,
Espèce(s)
mouse