Accéder au contenu
MilliporeSigma

CYP51A1

cytochrome P450, family 51, subfamily A, polypeptide 1

Synonymes:
CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1
Espèce(s):
Human CYP51A1 (1595), chicken CYP51A1 (420548), cow CYP51A1 (505060), dog CYP51A1 (475225)
ID UniProtKB:
Q16850, A4D1F8, B2RAI4, B4DJ55, O00770, O00772, Q16784, Q8N1A8
ID du gène:
  • Human(1595) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • chicken(420548) cytochrome P450, family 51, subfamily A, polypeptide 1
  • cow(505060) cytochrome P450, family 51, subfamily A, polypeptide 1
  • dog(475225) cytochrome P450, family 51, subfamily A, polypeptide 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Référence du produit
Description
Espèces réactives
Application
HPA041325
Anti-CYP51A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
western blot
MABS1259
Anti-CYP51A1 Antibody, clone N6-P2H5*G8, clone N6-P2H5*G8, from mouse,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
HPA043508
Anti-CYP51A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
SAB2107501
Anti-CYP51A1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
dog, guinea pig, horse, human, rat
Application
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
K1003
Ketoconazole, 99.0-101.0% (EP, titration),
Espèce(s)
mouse, human, rat
UC280
Ketoconazole, ,
Espèce(s)
mouse, human, rat

esiRNA

Référence du produit
Description
Espèce(s)
EHU105301
MISSION® esiRNA, targeting human CYP51A1, LRRD1,
Espèce(s)
human