CTSC
cathepsin C
Synonymes:
CPPI, DPP-I, DPP1, DPPI, HMS, JP, JPD, PALS, PDON1, PLS
Espèce(s):
Human CTSC (1075), Mouse Ctsc (13032), Rat Ctsc (25423), Zebrafish ctsc (368704), domestic cat CTSC (101092140), dog CTSC (403458), cow CTSC (352958), chicken CTSC (419014), sheep CTSC (101112686), domestic guinea pig Ctsc (100714387)
ID UniProtKB:
ID du gène:
- Human(1075) Summary: The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(13032) cathepsin C
- Rat(25423) cathepsin C
- Zebrafish(368704) cathepsin C
- domestic cat(101092140) cathepsin C
- dog(403458) cathepsin C
- cow(352958) cathepsin C
- chicken(419014) cathepsin C
- sheep(101112686) cathepsin C
- domestic guinea pig(100714387) cathepsin C
- naked mole-rat(101697606) cathepsin C
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-CTSC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-CTSC antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-Dipeptidyl-peptidase 1 (heavy chain, Cleaved-Arg394) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
ELISA
western blot
western blot
Proteins
Référence du produit
Description
Espèce(s)