CTNNB1
catenin (cadherin-associated protein), beta 1, 88kDa
Synonymes:
CTNNB, MRD19, armadillo
Espèce(s):
Human CTNNB1 (1499), Mouse Ctnnb1 (12387), Rat Ctnnb1 (84353), naked mole-rat Ctnnb1 (101720578), domestic guinea pig Ctnnb1 (100732604), sheep CTNNB1 (100294600), Domestic Rabbit CTNNB1 (100125985), Zebrafish ctnnb1 (30265), chicken CTNNB1 (395964), cow CTNNB1 (539003) ...Plus
ID UniProtKB:
ID du gène:
- Human(1499) Summary: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009]
- Mouse(12387) catenin (cadherin associated protein), beta 1
- Rat(84353) catenin (cadherin associated protein), beta 1
- naked mole-rat(101720578) catenin (cadherin-associated protein), beta 1, 88kDa
- domestic guinea pig(100732604) catenin (cadherin-associated protein), beta 1, 88kDa
- sheep(100294600) catenin (cadherin-associated protein), beta 1, 88kDa
- Domestic Rabbit(100125985) catenin (cadherin-associated protein), beta 1, 88kDa
- Zebrafish(30265) catenin (cadherin-associated protein), beta 1
- chicken(395964) catenin (cadherin-associated protein), beta 1, 88kDa
- cow(539003) catenin (cadherin-associated protein), beta 1, 88kDa
- Horse(100055241) catenin (cadherin-associated protein), beta 1, 88kDa
- domestic cat(101097342) catenin (cadherin-associated protein), beta 1, 88kDa
- dog(477032) catenin (cadherin-associated protein), beta 1, 88kDa
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Monoclonal Anti-β-Catenin antibody produced in mouse, clone 15B8, ascites fluid,
Espèces réactives
bovine, canine, chicken, human
Application
immunocytochemistry
immunofluorescence
immunohistochemistry
microarray
western blot
immunofluorescence
immunohistochemistry
microarray
western blot
Anti-β-Catenin−Cy3 antibody, Mouse monoclonal, clone 15B8, purified from hybridoma cell culture,
Espèces réactives
bovine, canine, chicken, human
Application
immunofluorescence
Monoclonal Anti-β-Catenin antibody produced in mouse, clone 6F9, ascites fluid,
Espèces réactives
bovine, canine, chicken, human
Application
immunofluorescence
microarray
western blot
microarray
western blot
Anti-CTNNB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CTNNB1 (Ab-33) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Cell Lines
Référence du produit
Description
Espèce(s)
Proteins
Référence du produit
Description
Espèce(s)
Catenin β, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human